The 33-year-old Swiss, ranked 261 in the world after two knee surgeries, served solidly throughout a one-sided contest on the slick centre court, easing past an opponent who struggled to cope with Wawrinka's power.
The volatile 17th seed had a quiet evening by his standards in his opening match on Monday, with just the one violation for unsportsmanlike behaviour when he asked spectator, in no uncertain terms, to be quiet while he was serving.
Andy Ram became the first Israeli to win a Grand Slam tennis title when he partnered Russia's Vera Zvonareva to win the Wimbledon mixed doubles crown.
In last year's quarter-finals at the All England Club, Federer saved three match points before edging out Cilic in five sets and the closeness of that match is comforting for the Croat.
"It was a weird start to my Centre Court. I hope the guy is all right," Kendrick said after the interruption to play.
French Open champion Rafael Nadal recovered from two sets down to beat American qualifier Robert Kendrick in the Wimbledon second round.
The Swiss has never been beyond the semi-finals at Roland Garros.
The 24-year-old, who has yet to win a Grand Slam title, was in stunning form as he defeated Russian Karen Khachanov 6-3, 6-1 to become the first German man to win a singles Olympic gold.
The problem with addictive TV box sets is that when the credits roll on the final episode it leaves a void.
With temperatures reaching almost 38 degrees on court, Murray, a twice Wimbledon champion, was beaten 7-6(4), 6-2 by Australian world number 90 Jordan Thompson.
A month shy of his 35th birthday, Roger Federer knows time is not on his side if he wants to triumph at Wimbledon again, but he is adamant his goals stretched beyond the world's most famous Centre Court.
Venus Williams carrying the hopes of the Williams clan while her younger sibling takes time out to have a baby.
After a 48-minute battering at the hands of Serena Williams on Wimbledon's Centre Court on Thursday, the last words Elena Vesnina probably wanted to hear were 'see you later'.
A preview of the Ladies semi-finals at Wimbledon.
The unseeded Croatian will contest his first Grand Slam semi-final at Wimbledon against either second seed Andy Roddick or number 12 Sjeng Schalken.
A round-up of the important matches at Wimbledon on Friday.
The world number 19 said her victory was reward for her father Walter.
IMAGES from Day 5 of the US Open, at the USTA Billie Jean King National Tennis Center, Flushing Meadows, New York, on Friday.
The Wimbledon champion crushed China's Li Na 6-0, 6-2 to become the fifth Russian woman to reach the fourth round.
The Wimbledon champions beat Australia's Samantha Stosur 6-2, 6-1 to enter the semi-finals of the Hansol Korea Open.
Wimbledon will herald a new men's champion and for the four players left in the draw, the moment has been a long time coming.
The Briton unleashed a furious verbal volley at the umpire during his match after a spectator called out during a rally in the third set.
Sharapova thanked her parents and paid special tribute to her father, who took her the US when she was seven.
Venus Williams, the 2000 and 2001 champion was shocked by Croatia's Karolina Sprem in the second round at Wimbledon.
Andre Agassi overcame a slow start to beat Boris Pashanski 2-6, 6-2, 6-4, 6-3 in the first round
Raducanu stormed into the third round of the Cincinnati Open
Madison Keys swept past Wimbledon champion Elena Rybakina 6-2, 6-4 at the Cincinnati Open on Friday, setting up a semi-final clash with Petra Kvitova after the Czech defeated Ajla Tomljanovic.
With the shock early exit of Hewitt and Agassi none of them has ever passed the semi-finals at Wimbledon.
American Andy Roddick and Briton Greg Rusedski will be going head-to-head on Centre Court in the race to hit the world's first 150 miles per hour (241.4 kph) serve.